Article
Novel frameshift mutation in STK33 is associated with asthenozoospermia and multiple morphological abnormalities of the flagella.
Human molecular genetics - 13 Oct 2021
Ma Hui, Zhang Beibei, Khan Asad, Zhao Daren, Ma Ao, Zhou Jianteng, Khan Ihsan, Khan Khalid, Zhang Huan, Zhang Yuanwei, Jiang Xiaohua, Dil Sobia, Zeb Aurang, Rahim Fazal, Shi Qinghua
Abstract excerpt
Serine/threonine kinases domain-containing proteins are known to play important functions in sperm flagella and male fertility. However, the roles of these proteins in human reproduction remain poorly understood and whether their variants are associated with human asthenozoospermia have not been reported. Here, we recruited a Pakistani family having four infertile patients diagnosed with idiopathic...
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