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Article

A novel variant in CFAP69 causes asthenoteratozoospermia with treatable ART outcomes and a literature review.

Journal of assisted reproduction and genetics - 1 Sept 2023

Tang Xiangrong, Ma Jing, Wang Xinglin, Long Shunhua, Wan Ling, Yu Haibing, Yang Jigao, Huang Guoning, Lin Tingting

Abstract excerpt

PURPOSE: Multiple morphological abnormalities of the sperm flagella (MMAF) are a severe form of sperm defect causing male infertility. Previous studies identified the variants in the CFAP69 gene as a MMAF-associated factor, but few cases have been reported. This study was performed to identify additional variants in CFAP69 and describe the semen characteristics and outcomes of assisted reproductive technology...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37392306
DOI: 10.1007/s10815-023-02873-1
PMCID: PMC10440328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel variant in CFAP69 causes asthenoteratozoospermia with treatable ART outcomes and a literature review.PMID 37392306Read ↗

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CFAP70 mutations lead to male infertility due to severe astheno-teratozoospermia. A case reportSemantic proximity Read ↗

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Absence of CFAP69 Causes Male Infertility due to Multiple Morphological Abnormalities of the Flagella in Human and Mouse.Semantic proximity Read ↗

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Biallelic CFAP61 variants cause male infertility in humans and mice with severe oligoasthenoteratozoospermiaSemantic proximity Read ↗

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