Article

Loss-of-function variant in TEX44 cause male infertility with asthenoteratozoospermia in humans and mice

2025-12-11

Abstract excerpt

<title>Abstract</title> <p>Background Asthenoteratozoospermia, characterized by impaired sperm motility and abnormal morphology, is a major cause of male infertility. However, its genetic basis remains largely unclear in many idiopathic cases. Testis-expressed protein 44 (TEX44) is critical for murine sperm flagellar development, but its role in human asthenoteratozoospermia is remains poorly defined. Methods Who...

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Literature Corpus work: 7614e41f-3029-5efb-955c-1431ce010386
DOI: 10.21203/rs.3.rs-8214156/v1

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