Article
IL-23R Variant rs11805303 Is Associated With Susceptibility to the Development of Cutaneous Leishmaniasis in Leishmania guyanensis-Infected Individuals.
The Journal of infectious diseases - 5 Jan 2022
Santos da Silva Lener, Santo Júnior José do Espírito, de Mesquita Tirza Gabrielle Ramos, Santos Veronica Alice Marinho, de Souza Josué Lacerda, de Araújo Felipe Jules, da Silveira Júnior Cláudio Marcello, da Silva Cilana Chagas, Queiroz Krys Layane Guimarães Duarte, Sequera Héctor David Graterol, Guerra Marcus Vinitius de Farias, de Souza Mara Lúcia Gomes, Ramasawmy Rajendranath
Abstract excerpt
BACKGROUND: Emerging evidence suggests that the interleukin (IL) 17/ IL-23 axis may play a role in the pathogenesis of leishmaniasis. Our aim was to investigate whether the IL-23R variant rs11805303 is a risk factor for the development of cutaneous leishmaniasis (CL) in Leishmania guyanensis-infected individuals. METHODS: We genotyped by polymerase chain reaction-restriction fragment length polymorphism the...
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