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Article

Evaluation of IL-12RB1, IL-12B, CXCR-3 and IL-17a expression in cases affected by a non-healing form of cutaneous leishmaniasis: an observational study design.

BMJ open - 27 Jan 2017

Moafi Mohammad, Rezvan Hossein, Sherkat Roya, Taleban Roya, Asilian Ali, Zarkesh Esfahani Seyed Hamid, Nilforoushzadeh Mohammad Ali, Jaffary Fariba, Feizi Awat

Abstract excerpt

INTRODUCTION: Seldom cutaneous leishmaniasis (CL) may present as a lasting and active lesion(s), known as a non-healing form of CL (NHCL). Non-functional type 1 T helper (Th1) cells are assumed the most important factor in the outcome of the disease. The present study aims to assess some molecular defects that potentially contribute to Th1 impairment in NHCL. METHODS AND ANALYSIS: This prospective observational...

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Identifiers

PMID: 28132002
DOI: 10.1136/bmjopen-2016-013006
PMCID: PMC5278291

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