Article
Inflammation as a regulator of hematopoietic stem cell function in disease, aging, and clonal selection
20 May 2021
Abstract excerpt
Inflammation is an evolutionarily selected defense response to infection or tissue damage that involves activation and consumption of immune cells in order to reestablish and maintain organismal integrity. In this process, hematopoietic stem cells (HSCs) are themselves exposed to inflammatory cues and via proliferation and differentiation, replace mature immune cells in a demand-adapted fashion. Here, we review...
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