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Inflammation, Aging and Hematopoiesis: A Complex Relationship

4 Jun 2021

Abstract excerpt

All vertebrate blood cells descend from multipotent hematopoietic stem cells (HSCs), whose activity and differentiation depend on a complex and incompletely understood relationship with inflammatory signals. Although homeostatic levels of inflammatory signaling play an intricate role in HSC maintenance, activation, proliferation, and differentiation, acute or chronic exposure to inflammation can have deleterious...

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Acute Myeloid Leukemia Research
Hematopoietic Stem Cell Transplantation
Immune cells in cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34199874
DOI: 10.3390/cells10061386

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