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Association of MTHFD Gene Polymorphisms and Maternal Smoking With Risk of Congenital Heart Disease: A Hospital-Based Case-Control Study

2021-07-15

Abstract excerpt

<h4>Background: </h4> MTHFD may affect the embryonic development by elevated homocysteine levels, DNA synthesis and DNA methylation, but limited number of genetic variants of MTHFD was focused on the association with congenital heart disease (CHD). This study examined the role of MTHFD and maternal smoking in CHD risk, and investigated their interaction effects in Chinese populations. <h4>Methods: </h4>: A case-co...

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Literature Corpus work
70e6a393-85af-5497-86bc-dc5ee42481db
DOI
10.21203/rs.3.rs-650881/v1
Open publication

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Association of MTHFD Gene Polymorphisms and Maternal Smoking With Risk of Congenital Heart Disease: A Hospital-Based Case-Control StudyDOI 10.21203/rs.3.rs-650881/v1
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