Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between maternal MTHFR and MTRR gene polymorphisms and the risk of congenital heart disease in newborns.

BMC pediatrics - 27 Mar 2026

Luo Shimu, Zhou Jianlin, Zhang Hegan, Lin Li, Zhang Zhishan, Chen Youfang

Abstract excerpt

BACKGROUND: Although numerous studies have explored the maternal genetic contributions to Congenital Heart Disease (CHD), their findings remain inconsistent. This study aimed to investigate the association between maternal gene polymorphisms and neonatal CHD risk in the Chinese Han population from southern Fujian. METHODS: We conducted a hospital-based case–control study between January 2023 and December 2024,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to China
Share to Ferredoxin-NADP Reductase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Defects, Congenital

Share to Infant, Newborn

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 41896807
DOI: 10.1186/s12887-026-06759-w
PMCID: PMC13147584

Genes

MTHFR
MTRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between maternal MTHFR and MTRR gene polymorphisms and the risk of congenital heart disease in newborns.PMID 41896807Read ↗

Association between maternal MTHFR and MTRR gene polymorphisms and the risk of congenital heart disease in newbornsSemantic proximity Read ↗

Association of maternal methionine synthase reductase gene polymorphisms with the risk of congenital heart disease in offspring: a hospital-based case-control study.Semantic proximity Read ↗

Association analysis of maternal MTHFR gene polymorphisms and the occurrence of congenital heart disease in offspring.Semantic proximity Read ↗

[Association of maternal MTHFD1 and MTHFD2 gene polymorphisms with congenital heart disease in offspring].Semantic proximity Read ↗

[Association between maternal reduced folate carrier gene polymorphisms and congenital heart disease in offspring: a case-control study].Semantic proximity Read ↗

Association of maternal folic acid supplementation and offspring MTRR gene polymorphism with congenital heart disease: a hospital-based case-control study in Han populationSemantic proximity Read ↗

Association of MTR gene polymorphisms with the occurrence of non-syndromic congenital heart disease: a case-control study.Semantic proximity Read ↗

Association of maternal folic acid supplementation and offspring MTRR gene polymorphism with congenital heart disease: a hospital-based case-control study in Han population.Semantic proximity Read ↗

Association between MTR A2756G polymorphism and susceptibility to congenital heart disease: A meta-analysis.Semantic proximity Read ↗

Association of MTHFD1 gene polymorphisms and maternal smoking with risk of congenital heart disease: a hospital-based case-control study.Semantic proximity Read ↗

Association between MTHFR polymorphisms and congenital heart disease: a meta-analysis based on 9,329 cases and 15,076 controls.Semantic proximity Read ↗

The Roles of Reduced Folate Carrier-1 (RFC1) A80G (rs1051266) Polymorphism in Congenital Heart Disease: A Meta-Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.