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Article

HLA-associated adverse drug reactions - scoping review.

Clinical and translational science - 1 Sept 2021

Jeiziner Chiara, Wernli Ursina, Suter Katja, Hersberger Kurt E, Meyer Zu Schwabedissen Henriette E

Abstract excerpt

Alleles of the human leukocyte antigen (HLA) system have been associated with the occurrence of idiosyncratic adverse drug reactions (ADRs). Accordingly, it is assumed that pre-emptive testing for the presence of certain HLA alleles (HLA-typing) could prevent these ADRs in carriers. In order to perceive the current evidence for HLA-associated ADRs, we conducted a scoping review according to the Preferred...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34105877
DOI: 10.1111/cts.13062
PMCID: PMC8504845

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