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Update on HLA-B*15:02 allele associated with adverse drug reactions.

Pharmacogenomics - 1 Jan 2024

Zhu Xueting, Luo Guanghua, Zheng Lu

Abstract excerpt

HLA alleles, part of the major histocompatibility complex, are strongly associated with adverse drug reactions (ADRs). This review focuses on HLA-B*15:02 and explores its association with ADRs in various ethnic populations and with different drugs, aiming to provide insights into the safe clinical use of drugs and minimize the occurrence of ADRs. Furthermore, the review explores the potential mechanisms by which...

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PMID: 38305022
DOI: 10.2217/pgs-2023-0173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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