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Article

Genetic polymorphisms of phase I and phase II metabolic enzymes as modulators of lung cancer susceptibility.

Journal of cancer research and clinical oncology - 1 May 2015

Mota P, Silva H C, Soares M J, Pego A, Loureiro M, Cordeiro C Robalo, Regateiro F J

Abstract excerpt

OBJECTIVES: Tobacco exposure remains the main etiologic factor for lung cancer (LC). Interactions between environment and individual genetic profile are particularly important for this disease. The aim of this study was to evaluate the contribution of CYP1A1*2A, CYP1A1*2C, CYP2D6*4, GSTP1, GSTM1, GSTT1 and NAT2 polymorphisms for the susceptibility to LC in a Portuguese population considering their demographic and...

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Source

Identifiers

PMID: 25388590
DOI: 10.1007/s00432-014-1868-z

Genes

GSTP1
GSTT1
NAT2
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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