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Article

Multiple analytical approaches reveal distinct gene-environment interactions in smokers and non smokers in lung cancer.

PloS one - 1 Jan 2011

Ihsan Rakhshan, Chauhan Pradeep Singh, Mishra Ashwani Kumar, Yadav Dhirendra Singh, Kaushal Mishi, Sharma Jagannath Dev, Zomawia Eric, Verma Yogesh, Kapur Sujala, Saxena Sunita

Abstract excerpt

Complex disease such as cancer results from interactions of multiple genetic and environmental factors. Studying these factors singularly cannot explain the underlying pathogenetic mechanism of the disease. Multi-analytical approach, including logistic regression (LR), classification and regression tree (CART) and multifactor dimensionality reduction (MDR), was applied in 188 lung cancer cases and 290 controls to...

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Share to Cytochrome P-450 CYP1A1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22206016
DOI: 10.1371/journal.pone.0029431
PMCID: PMC3242784

Genes

EPHX1
GSTP1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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