Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synergistic association of PTGS2 and CYP2E1 genetic polymorphisms with lung cancer risk in northeastern Chinese.

PloS one - 1 Jan 2012

Guo Shujie, Li Xiaobo, Gao Min, Kong Hong, Li Yuqiong, Gu Mingliang, Dong Xiaoqun, Niu Wenquan

Abstract excerpt

BACKGROUND: Lung cancer is the most common cause of cancer-related deaths worldwide. The aim of this study was to investigate the association of five extensively-studied polymorphisms in PTGS2 (rs689466, rs5275, rs20417) and CYP2E1 (rs2031920, rs6413432) genes with lung cancer risk in a large northeastern Chinese population. METHODOLOGY/PRINCIPAL FINDINGS: This is a hospital-based case-control study involving 684...

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to China
Share to Cyclooxygenase 2
Share to Cytochrome P-450 CYP2E1
Share to Genetic Association Studies
Share to Haplotypes
Share to Lung Neoplasms
Share to Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 22761909
DOI: 10.1371/journal.pone.0039814
PMCID: PMC3382578

Genes

PTGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synergistic association of PTGS2 and CYP2E1 genetic polymorphisms with lung cancer risk in northeastern Chinese.PMID 22761909Read ↗

A Large-Scale Genome-Wide Gene-Gene Interaction Study of Lung Cancer Susceptibility in Europeans With a Trans-Ethnic Validation in Asians.Semantic proximity Read ↗

CYP4F2 And CYP3A5 Gene Polymorphisms And Lung Cancer In Chinese Han PopulationSemantic proximity Read ↗

CYP4F2 and CYP3A5 gene polymorphisms and lung cancer in Chinese Han population.Semantic proximity Read ↗

Glutathione S-transferase P1, gene-gene interaction, and lung cancer susceptibility in the Chinese population: An updated meta-analysis and review.Semantic proximity Read ↗

Polymorphisms of COX/PEG2 pathway-related genes are associated with the risk of lung cancer: A case-control study in China.Semantic proximity Read ↗

Genetic susceptibility of lung cancer in Chinese population: An overview of systematic reviews and meta-analyses.Semantic proximity Read ↗

Synergistic polymorphic interactions of phase II metabolizing genes and their association toward lung cancer susceptibility in North Indians.Semantic proximity Read ↗

Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies.Semantic proximity Read ↗

Missense variants in CYP4B1 associated with increased risk of lung cancer among Chinese Han population.Semantic proximity Read ↗

Association between CYP2A13 polymorphisms and lung cancer: A protocol for systematic review and meta-analysis.Semantic proximity Read ↗

Correlation between gene polymorphisms of CYP1A1, GSTP1, ERCC2, XRCC1, and XRCC3 and susceptibility to lung cancer.Semantic proximity Read ↗

Impact of COL6A4P2 gene polymorphisms on the risk of lung cancer: A case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.