Article
The effect of CYP, GST, and SULT polymorphisms and their interaction with smoking on the risk of hepatocellular carcinoma.
BioMed research international - 1 Jan 2015
Boccia Stefania, Miele Luca, Panic Nikola, Turati Federica, Arzani Dario, Cefalo Consuelo, Amore Rosarita, Bulajic Milutin, Pompili Maurizio, Rapaccini Gianlodovico, Gasbarrini Antonio, La Vecchia Carlo, Grieco Antonio
Abstract excerpt
Aim. The aim of our study was to assess whether selected single nucleotide polymorphisms of CYP1A1 and 2E1, GSTM1, GSTT1, and SULT1A1 influence susceptibility towards HCC, considering their interaction with cigarette smoking. Methods. We recruited HCC cases and controls among patients admitted to the hospital "Agostino Gemelli," from January 2005 until July 2010. Odds ratios (OR) of HCC were derived from...
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