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Article

Dhx15 regulates zebrafish definitive hematopoiesis through the unfolded protein response pathway.

Cancer science - 1 Sept 2021

Cai Yuanhua, Wang Jing, Jin Daqing, Liu Qiao, Chen Xianglei, Pan Lili, Li Yang, Wang Xuechun, Qian Feng, Wang Jiucun, Zhong Tao Peter, Wang Shaoyuan

Abstract excerpt

Gene alterations are recognized as important events in acute myeloid leukemia (AML) progression. Studies on hematopoiesis of altered genes contribute to a better understanding on their roles in AML progression. Our previous work reported a DEAH box helicase 15 (DHX15) R222G mutation in AML patients, and we showed DHX15 overexpression is associated with poor prognosis in AML patients. In this work, we further...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34077586
DOI: 10.1111/cas.15002
PMCID: PMC8409414

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