Article

Identification of Dhx15 as a Major Regulator of Liver Development, Regeneration and Tumor Growth in Zebrafish and Mice

2024-01-10

Abstract excerpt

<h4>Background: </h4> RNA helicase DHX15 plays a significant role in vasculature development and lung metastasis in vertebrates. In addition, several studies have demonstrated the overexpression of DHX15 in the context of hepatocellular carcinoma. Therefore, we hypothesized that this helicase may play a significant role in liver regeneration, physiology and pathology. <h4>Methods:</h4> Dhx15 gene deficiency was ge...

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Literature Corpus work: 0ff789bc-193f-54cb-9f2a-bf311c00e7d2
DOI: 10.20944/preprints202401.0766.v1

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