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Article

Influence of NKG2C Genotypes on HIV Susceptibility and Viral Load Set Point.

Journal of virology - 26 Jul 2021

Alsulami Khlood, Bolastig Naomi, Dupuy Franck P, Mabanga Tsoarello, Gilbert Louise, Kiani Zahra, Routy Jean-Pierre, Bruneau Julie, Thomas Réjean, Tremblay Cécile, Tsoukas Christos M, Szabo Jason, Côté Pierre, Trottier Benoit, LeBlanc Roger, Rouleau Danielle, Bernard Nicole F

Abstract excerpt

NKG2C is an activating NK cell receptor encoded by a gene having an unexpressed deletion variant. Cytomegalovirus (CMV) infection expands a population of NKG2C+ NK cells with adaptive-like properties. Previous reports found that carriage of the deleted NKG2C- variant was more frequent in people living with HIV (PLWH) than in HIV- controls unexposed to HIV. The frequency of NKG2C+ NK cells positively correlated...

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Share to Coinfection
Share to Cytomegalovirus Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to HIV Infections

Share to HIV Seronegativity

Share to Killer Cells, Natural

Share to NK Cell Lectin-Like Receptor Subfamily C

Share to Viral Load

Source

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Identifiers

PMID: 34076484
DOI: 10.1128/JVI.00417-21
PMCID: PMC8312870

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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