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Article

Subordinate Effect of -21M HLA-B Dimorphism on NK Cell Repertoire Diversity and Function in HIV-1 Infected Individuals of African Origin.

Frontiers in immunology - 1 Jan 2020

Cubero Elia Moreno, Ogbe Ane, Pedroza-Pacheco Isabela, Cohen Myron S, Haynes Barton F, Borrow Persephone, Peppa Dimitra

Abstract excerpt

Natural Killer (NK) cells play an important role in antiviral defense and their potent effector function identifies them as key candidates for immunotherapeutic interventions in chronic viral infections. Their remarkable functional agility is achieved by virtue of a wide array of germline-encoded inhibitory and activating receptors ensuring a self-tolerant and tunable repertoire. NK cell diversity is generated by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32132995
DOI: 10.3389/fimmu.2020.00156
PMCID: PMC7041644

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Subordinate Effect of -21M HLA-B Dimorphism on NK Cell Repertoire Diversity and Function in HIV-1 Infected Individuals of African Origin.PMID 32132995Read ↗

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