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Whole-exome sequencing identifies somatic mutations and intratumor heterogeneity in inflammatory breast cancer

1 Jun 2021

Abstract excerpt

Inflammatory breast cancer (IBC) is the most aggressive form of breast cancer. Although it is a rare subtype, IBC is responsible for roughly 10% of breast cancer deaths. In order to obtain a better understanding of the genomic landscape and intratumor heterogeneity (ITH) in IBC, we conducted whole-exome sequencing of 16 tissue samples (12 tumor and four normal samples) from six hormone-receptor-positive IBC...

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PMID: 34075047
DOI: 10.1038/s41523-021-00278-w

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