HOXB13 mutation and prostate cancer: studies of siblings and aggressive disease.

doi:10.1158/1055-9965.EPI-12-1154

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

HOXB13 mutation and prostate cancer: studies of siblings and aggressive disease.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2013

Witte John S, Mefford Joel, Plummer Sarah J, Liu Jinghua, Cheng Iona, Klein Eric A, Rybicki Benjamin A, Casey Graham

Abstract excerpt

BACKGROUND: Recent work detected for the first time a high-risk prostate cancer mutation, in homeobox B13 (HOXB13) among European-Americans. METHODS: We further evaluated this G84E missense mutation (rs138213197) in two genetic association studies of prostate cancer: a family-based study of brothers and a case-control study of more aggressive disease (N = 2,665 total). We then calculated overall impact of this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeodomain Proteins

Share to Neoplasm Grading

Share to Neoplasm Staging

Share to Prognosis

Share to Prostate

Share to Prostatic Neoplasms

Share to Siblings

Source

Open in PubMed Open full text

Identifiers

PMID: 23396964
DOI: 10.1158/1055-9965.EPI-12-1154
PMCID: PMC3617049

Genes

HOXB13
IMPACT

Variants

rs138213197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HOXB13 mutation and prostate cancer: studies of siblings and aggressive disease.PMID 23396964Read ↗

Germline Mutations in HOXB13 and Prostate-Cancer RiskSemantic proximity Read ↗

HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG).Semantic proximity Read ↗

G84E mutation in HOXB13 is firmly associated with prostate cancer risk: a meta-analysis.Semantic proximity Read ↗

Homeobox B13 G84E Mutation and Prostate Cancer RiskSemantic proximity Read ↗

Prostate cancer risk variants of the HOXB genetic locus.Semantic proximity Read ↗

Confirmation of the HOXB13 G84E germline mutation in familial prostate cancer.Semantic proximity Read ↗

Population-Based Estimate of Prostate Cancer Risk for Carriers of the HOXB13 Missense Mutation G84ESemantic proximity Read ↗

The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: results from the REDUCE trial.Semantic proximity Read ↗

Association of HOXB13 G84E With Prostate Cancer Among 592,158 Men.Semantic proximity Read ↗

Germline homeobox B13 (HOXB13) G84E mutation and prostate cancer risk in European descendants: a meta-analysis of 24,213 cases and 73, 631 controls.Semantic proximity Read ↗

Prevalence of the HOXB13 G84E mutation in Danish men undergoing radical prostatectomy and its correlations with prostate cancer risk and aggressiveness.Semantic proximity Read ↗

Inherited Predisposition to Prostate Cancer: From Gene Discovery to Clinical Impact.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.