Confirmation of the HOXB13 G84E germline mutation in familial prostate cancer.

doi:10.1158/1055-9965.EPI-12-0495

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Confirmation of the HOXB13 G84E germline mutation in familial prostate cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2012

Breyer Joan P, Avritt T Grant, McReynolds Kate M, Dupont William D, Smith Jeffrey R

Abstract excerpt

BACKGROUND: A recent study of familial and early onset prostate cancer reported a recurrent rare germline mutation of HOXB13 among men of European descent. The gene resides within the 17q21 hereditary prostate cancer linkage interval. METHODS: We evaluated the G84E germline mutation (rs138213197) of HOXB13 in a case-control study of familial prostate cancer at Vanderbilt University (Nashville, TN) to...

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PMID: 22714738
DOI: 10.1158/1055-9965.EPI-12-0495
PMCID: PMC3415588

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HOXB13
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