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Article

Case series of diffuse extraneural metastasis in H3F3A mutant high-grade gliomas: Clinical, molecular phenotype and literature review.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Jul 2021

Mohiuddin Sana, Maraka Stefania, Usman Baig Muhammad, Gupta Sumit, Muzzafar Tariq, Valyi-Nagy Tibor, Lindsay Holly, Moody Karen, Razvi Shehla, Paulino Arnold, Slavin Konstantin, Gondi Vinai, McCutcheon Ian, Zaky Wafik, Khatua Soumen

Abstract excerpt

H3K27M and H3.3G34R/V mutations have been identified in pediatric high-grade gliomas (pHGG), though extraneural metastases are rarely reported and poorly characterized. Three pHGG patients from two institutions were identified with extraneural metastasis, harboring histone mutations. Their clinical, imaging and molecular characteristics are reported here. A 17-year old female presented with supratentorial...

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PMID: 34053821
DOI: 10.1016/j.jocn.2021.05.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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