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Article

Adult Brainstem Gliomas With H3K27M Mutation: Radiology, Pathology, and Prognosis.

Journal of neuropathology and experimental neurology - 1 Apr 2018

Daoud Elena V, Rajaram Veena, Cai Chunyu, Oberle Robert J, Martin Gregory R, Raisanen Jack M, White Charles L, Foong Chan, Mickey Bruce E, Pan Edward, Hatanpaa Kimmo J

Abstract excerpt

Adult brainstem gliomas are difficult to classify based on radiologic and histologic features. A K27M mutation in histone 3 has been described to identify high-grade midline gliomas associated with a particularly unfavorable prognosis. While initially considered a pediatric entity, it is now known that H3K27M-mutant brainstem gliomas occur in all age groups, but they are less well understood in adults. We studied...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29444279
DOI: 10.1093/jnen/nly006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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