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Article

H3 K27M-mutant gliomas in adults vs. children share similar histological features and adverse prognosis.

Clinical neuropathology - 1 Jan 2000

Kleinschmidt-DeMasters Bette K, Mulcahy Levy Jean M

Abstract excerpt

BACKGROUND: H3 K27M mutation was originally described in pediatric diffuse intrinsic pontine gliomas (DIPGs), but has been recently recognized to occur also in adult midline diffuse gliomas, as well as midline tumors with other morphologies, including gangliogliomas (GGs), anaplastic GGs, pilocytic astrocytomas (PAs), and posterior fossa ependymomas. In a few patients with H3 K27M;mutant tumors with these...

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Identifiers

PMID: 29393845
DOI: 10.5414/NP301085
PMCID: PMC5822176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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