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Aurora kinase A, a synthetic lethal target for precision cancer medicine

1 May 2021

Abstract excerpt

Recent advances in high-throughput sequencing technologies and data science have facilitated the development of precision medicine to treat cancer patients. Synthetic lethality is one of the core methodologies employed in precision cancer medicine. Synthetic lethality describes the phenomenon of the interplay between two genes in which deficiency of a single gene does not abolish cell viability but combined...

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PMID: 34050264
DOI: 10.1038/s12276-021-00635-6

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