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Article

FDG-PET in presymptomatic C9orf72 mutation carriers.

NeuroImage. Clinical - 1 Jan 2021

Popuri Karteek, Beg Mirza Faisal, Lee Hyunwoo, Balachandar Rakesh, Wang Lei, Sossi Vesna, Jacova Claudia, Baker Matt, Shahinfard Elham, Rademakers Rosa, Mackenzie Ian R A, Hsiung Ging-Yuek R

Abstract excerpt

OBJECTIVE: Our aim is to investigate patterns of brain glucose metabolism using fluorodeoxyglucose positron emission tomography (FDG-PET) in presymptomatic carriers of the C9orf72 repeat expansion to better understand the early preclinical stages of frontotemporal dementia (FTD). METHODS: Structural MRI and FDG-PET were performed on clinically asymptomatic members of families with FTD caused by the C9orf72 repeat...

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Identifiers

PMID: 34049163
DOI: 10.1016/j.nicl.2021.102687
PMCID: PMC8170157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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