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Article

Tests of association based on genomic windows can lead to spurious associations when using genotype panels with heterogeneous SNP densities.

Genetics, selection, evolution : GSE - 26 May 2021

Li Jinghui, Wang Zigui, Fernando Rohan, Cheng Hao

Abstract excerpt

Dense single nucleotide polymorphism (SNP) panels are widely used for genome-wide association studies (GWAS). In these panels, SNPs within a genomic segment tend to be highly correlated. Thus, association studies based on testing the significance of single SNPs are not very effective, and genomic-window based tests have been proposed to address this problem. However, when the SNP density on the genotype panel is...

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PMID: 34039266
DOI: 10.1186/s12711-021-00638-x
PMCID: PMC8157676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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