Detecting haplotype effects in genomewide association studies.

doi:10.1002/gepi.20242

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Article

Detecting haplotype effects in genomewide association studies.

Genetic epidemiology - 1 Dec 2007

Huang B E, Amos C I, Lin D Y

Abstract excerpt

The analysis of genomewide association studies requires methods that are both computationally feasible and statistically powerful. Given the large-scale collection of single nucleotide polymorphisms (SNPs), it is desirable to explore the information contained in their interrelationships. In particular, utilizing haplotypes rather than individual SNPs and accounting for correlations of polymorphisms in adjustment...

Topics

Adolescent
Adult
Algorithms
Arthritis, Rheumatoid
Case-Control Studies
Chromosomes, Human, Pair 18
Computer Simulation
Data Interpretation, Statistical
Female
Genetic Diseases, Inborn
Genome, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Haplotypes

Humans

Likelihood Functions

Male

Middle Aged

Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 17549762
DOI: 10.1002/gepi.20242

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-17549762-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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