Article
Matching strategies for genetic association studies in structured populations.
American journal of human genetics - 1 Feb 2004
Hinds David A, Stokowski Renee P, Patil Nila, Konvicka Karel, Kershenobich David, Cox David R, Ballinger Dennis G
Abstract excerpt
Association studies in populations that are genetically heterogeneous can yield large numbers of spurious associations if population subgroups are unequally represented among cases and controls. This problem is particularly acute for studies involving pooled genotyping of very large numbers of si...
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