Article
Heterochronic evolution reveals modular timing changes in budding yeast transcriptomes.
Genome biology - 1 Jan 2010
Simola Daniel F, Francis Chantal, Sniegowski Paul D, Kim Junhyong
Abstract excerpt
BACKGROUND: Gene expression is a dynamic trait, and the evolution of gene regulation can dramatically alter the timing of gene expression without greatly affecting mean expression levels. Moreover, modules of co-regulated genes may exhibit coordinated shifts in expression timing patterns during evolutionary divergence. Here, we examined transcriptome evolution in the dynamical context of the budding yeast...
Topics
- Cell Cycle
- Evolution, Molecular
- Gene Expression Profiling
- Gene Expression Regulation, Fungal
- Gene Regulatory Networks
- Genetic Variation
- Oligonucleotide Array Sequence Analysis
- RNA, Fungal
- Saccharomyces cerevisiae
- Transcription Factors