Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetics and microRNAs in UGT1As

25 May 2021

Abstract excerpt

UDP-glucuronosyltransferases (UGTs) are the main phase II drug-metabolizing enzymes mediating the most extensive glucuronidation-binding reaction in the human body. The UGT1A family is involved in more than half of glucuronidation reactions. However, significant differences exist in the distribution of UGT1As in vivo and the expression of UGT1As among individuals, and these differences are related to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Neonatal Respiratory Health Research
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34034810
DOI: 10.1186/s40246-021-00331-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetics and microRNAs in UGT1AsPMID 34034810Read ↗

UGT pharmacogenomicsSemantic proximity Read ↗

UGT pharmacogenomics: implications for cancer risk and cancer therapeutics.Semantic proximity Read ↗

UGT genomic diversity: beyond gene duplication.Semantic proximity Read ↗

Histone acetylation at the sulfotransferase 1a1 gene is associated with its hepatic expression in normal agingSemantic proximity Read ↗

Variability and function of family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A).Semantic proximity Read ↗

Genetic factors affecting gene transcription and catalytic activity of UDP-glucuronosyltransferases in human liver.Semantic proximity Read ↗

Family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A): from Gilbert's syndrome to genetic organization and variability.Semantic proximity Read ↗

Epigenetics and MicroRNAs in Pharmacogenetics.Semantic proximity Read ↗

Polymorphism of UDP-Glucuronosyltransferase and Drug MetabolismSemantic proximity Read ↗

Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs, gut microbiota, and diseases: a meeting report of the 21st International Symposium on Microsomes and Drug Oxidations (MDO)Semantic proximity Read ↗

Genetic variability, haplotypes, and htSNPs for exons 1 at the human UGT1A locus.Semantic proximity Read ↗

Evidence for regulation of UDP-glucuronosyltransferase (UGT) 1A1 protein expression and activity via DNA methylation in healthy human livers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.