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Article

Steroid 21-hydroxylase gene variants and late-life depression.

BMC research notes - 25 May 2021

Ancelin Marie-Laure, Norton Joanna, Ritchie Karen, Chaudieu Isabelle, Ryan Joanne

Abstract excerpt

OBJECTIVES: A feature of late-life depression is alterations of the stress hormone system. The CYP21A2 gene encodes for the steroid 21-hydroxylase enzyme which is required for the biosynthesis of mineralocorticoids and glucocorticoids, two main components of the stress response in humans. Variants in the CYP21A2 gene could influence risk of late-life depression, but this has not been examined. This study...

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Identifiers

PMID: 34034803
DOI: 10.1186/s13104-021-05616-6
PMCID: PMC8147346

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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