Article
Pharmacogenetic considerations for late life depression therapy.
Expert opinion on drug metabolism & toxicology - 1 Aug 2013
Pitychoutis Pothitos M, Kokras Nikolaos, Sanoudou Despina, Dalla Christina, Papadopoulou-Daifoti Zeta
Abstract excerpt
INTRODUCTION: Geriatric depression is a heterogeneous disorder with a complex genetic background. Current first-line treatment of depression is associated with a lower therapeutic outcome in aged depressed patients, when compared to younger subjects. Research which has explored this inadequate response has highlighted several factors which have come into play with the pharmacogenetics of antidepressants in the...
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