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Article

Hormonal determinants and effect of ER22/23EK glucocorticoid receptor gene polymorphism on health status deterioration in the participants of the Mataró Ageing Study.

Age (Dordrecht, Netherlands) - 1 Jun 2012

Mora Mireia, Sánchez Lidia, Serra-Prat Mateu, Palomera Elisabet, Blanco Jesús, Aranda Gloria, Falcón Immaculada, Cadenas Immaculada, Boquet Xavier, Oriola Josep, Puig-Domingo Manuel

Abstract excerpt

The purpose of this study is to assess the potential relationships of circulating IGF-I, adrenal and gonadal steroids, and polymorphism ER22/23EK of the glucocorticoid receptor (GC-R) gene with nutritional, functional and cognitive deterioration in a group of elderly people living independently. This is a population-based prospective study with 313 individuals (160 women and 153 men, 76.7 ± 7 years) who...

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PMID: 21544576
DOI: 10.1007/s11357-011-9255-z
PMCID: PMC3337942

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