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Article

ERp44/CG9911 promotes fat storage in Drosophila adipocytes by regulating ER Ca2+ homeostasis.

Aging - 24 May 2021

Bi Youkun, Chang Yan, Liu Qun, Mao Yang, Zhai Kui, Zhou Yuanli, Jiao Renjie, Ji Guangju

Abstract excerpt

Fat storage is one of the important strategies employed in regulating energy homeostasis. Impaired lipid storage causes metabolic disorders in both mammals and Drosophila. In this study, we report CG9911, the Drosophila homolog of ERp44 (endoplasmic reticulum protein 44) plays a role in regulating adipose tissue fat storage. Using the CRISPR/Cas9 system, we generated a CG9911 mutant line deleting 5 bp of the...

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Identifiers

PMID: 34031268
DOI: 10.18632/aging.203063
PMCID: PMC8221293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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