Article
C elegans: a model for exploring the genetics of fat storage.
Developmental cell - 1 Jan 2003
McKay Renée M, McKay James P, Avery Leon, Graff Jonathan M
Abstract excerpt
To gain insights into the genetic cascades that regulate fat biology, we evaluated C. elegans as an appropriate model organism. We generated worms that lack two transcription factors, SREBP and C/EBP, crucial for formation of mammalian fat. Worms deficient in either of these genes displayed a lip...
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