Article
Functional genomic screen reveals genes involved in lipid-droplet formation and utilization.
Nature - 29 May 2008
Guo Yi, Walther Tobias C, Rao Meghana, Stuurman Nico, Goshima Gohta, Terayama Koji, Wong Jinny S, Vale Ronald D, Walter Peter, Farese Robert V
Abstract excerpt
Eukaryotic cells store neutral lipids in cytoplasmic lipid droplets enclosed in a monolayer of phospholipids and associated proteins. These dynamic organelles serve as the principal reservoirs for storing cellular energy and for the building blocks for membrane lipids. Excessive lipid accumulatio...
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