Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasmodium vivax vaccine candidate MSP1 displays conserved B-cell epitope despite high genetic diversity.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2021

Ghoshal Sharmistha, Datta Kanjilal Sumana, Sengupta Sanghamitra

Abstract excerpt

The polymorphic nature of merozoite surface protein 1(MSP1) raises doubts whether it may serve as a vaccine target against Plasmodium vivax malaria. This study analyses the impact of genetic variability on the epitope organization of different Pvmsp1 blocks. Ten blood samples collected from P. vivax infected malaria patients from West Bengal, India were used to analyze sequence and antigenic diversities of block...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epitopes, B-Lymphocyte
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Malaria Vaccines

Share to Merozoite Surface Protein 1

Share to Plasmodium vivax

Source

Identifiers

PMID: 34022438
DOI: 10.1016/j.meegid.2021.104929

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasmodium vivax vaccine candidate MSP1 displays conserved B-cell epitope despite high genetic diversity.PMID 34022438Read ↗

Diversity analysis of MSP1 identifies conserved epitope organization in block 2 amidst high sequence variability in Indian Plasmodium falciparum isolatesSemantic proximity Read ↗

Genetic diversity in the block 2 region of the merozoite surface protein-1 of Plasmodium falciparum in central India.Semantic proximity Read ↗

Extreme Genetic Diversity and Signatures of Balancing Selection in Plasmodium vivax Blood-Stage Antigens.Semantic proximity Read ↗

Genetic Diversity and Natural Selection of Plasmodium vivax Merozoite Surface Protein 8 in Global Populations.Semantic proximity Read ↗

Genetic diversity of MSP1 Block 2 of Plasmodium vivax isolates from Manaus (central Brazilian Amazon).Semantic proximity Read ↗

Genetic diversity of Merozoite surface protein 1-42 (MSP1-42) fragment of Plasmodium vivax from Indonesian isolates: Rationale implementation of candidate MSP1 vaccine.Semantic proximity Read ↗

Global Population Structure of the Genes Encoding the Malaria Vaccine Candidate, Plasmodium vivax Apical Membrane Antigen 1 (PvAMA1).Semantic proximity Read ↗

Genetic diversity and recombination at the C-terminal fragment of the merozoite surface protein-1 of Plasmodium vivax (PvMSP-1) in Sri Lanka.Semantic proximity Read ↗

Plasmodium falciparum: genetic diversity of C-terminal region of MSP-1 in isolates from Indian sub-continent.Semantic proximity Read ↗

Genetic diversity and population structure of genes encoding vaccine candidate antigens of Plasmodium vivaxSemantic proximity Read ↗

Structural patterns of selection and diversity for Plasmodium vivax antigens DBP and AMA1.Semantic proximity Read ↗

Population genetic analyses inferred a limited genetic diversity across the pvama-1 DI domain among Plasmodium vivax isolates from Khyber Pakhtunkhwa regions of Pakistan.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.