Article
Plasmodium falciparum: genetic diversity of C-terminal region of MSP-1 in isolates from Indian sub-continent.
Experimental parasitology - 1 Aug 2005
Vijay Kumar S, Ranjan Sarita, Saxena Vishal, Rajesh Vidya, Roy S K, Kochar Dhanpat, Ranjan Akash, Das Ashis
Abstract excerpt
Malaria parasites exhibit sequence diversity for a number of stage specific antigens. Several studies have proved that merozoite surface protein-1 (MSP-1) is an effective target eliciting a protective immune response. The MSP-1(42) region comprising two EGF-like domains is involved in generating protective immune response in humans and other experimental animals. Searching for point mutations in this region is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
