Article
Genome-wide association study of early-onset bipolar I disorder in the Han Taiwanese population.
Translational psychiatry - 20 May 2021
Wu Lawrence Shih-Hsin, Huang Ming-Chyi, Fann Cathy Shen-Jang, Lane Hsien-Yuan, Kuo Chian-Jue, Chiu Wei-Che, Kwok Pui-Yan, Cheng Andrew Tai-Ann
Abstract excerpt
The search for susceptibility genes underlying the heterogeneous bipolar disorder has been inconclusive, often with irreproducible results. There is a hope that narrowing the phenotypes will increase the power of genetic analysis. Early-onset bipolar disorder is thought to be a genetically homogeneous subtype with greater symptom severity. We conducted a genome-wide association study (GWAS) for this subtype in...
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