Article
Genome-wide association study of bipolar I disorder in the Han Chinese population.
Molecular psychiatry - 1 May 2011
Lee M T M, Chen C H, Lee C S, Chen C C, Chong M Y, Ouyang W C, Chiu N Y, Chuo L J, Chen C Y, Tan H K L, Lane H Y, Chang T J, Lin C H, Jou S H, Hou Y M, Feng J, Lai T J, Tung C L, Chen T J, Chang C J, Lung F W, Chen C K, Shiah I S, Liu C Y, Teng P R, Chen K H, Shen L J, Cheng C S, Chang T P, Li C F, Chou C H, Chen C Y, Wang K H T, Fann C S J, Wu J Y, Chen Y T, Cheng A T A
Abstract excerpt
We report the first genome-wide association study in 1000 bipolar I patients and 1000 controls, with a replication of the top hits in another 409 cases and 1000 controls in the Han Chinese population. Four regions with most strongly associated single-nucleotide polymorphisms (SNPs) were detected, of which three were not found in previous GWA studies in the Caucasian populations. Among them, SNPs close to...
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