European collaborative study of early-onset bipolar disorder: Evidence for genetic heterogeneity on 2q14 according to age at onset.

doi:10.1002/ajmg.b.31121

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

European collaborative study of early-onset bipolar disorder: Evidence for genetic heterogeneity on 2q14 according to age at onset.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2010

Mathieu Flavie, Dizier Marie-Hélène, Etain Bruno, Jamain Stéphane, Rietschel Marcella, Maier Wolfgang, Albus Margot, McKeon Patrick, Roche Siobhan, Blackwood Douglas, Muir Walter J, Henry Chantal, Malafosse Alain, Preisig Martin, Ferrero François, Cichon Sven, Schumacher Johannes, Ohlraun Stephanie, Propping Peter, Abou Jamra Rami, Schulze Thomas G, Zelenica Diana, Charon Céline, Marusic Andrej, Dernovsek Mojca C, Gurling Hugh, Nöthen Markus, Lathrop Mark, Leboyer Marion, Bellivier Frank

Abstract excerpt

Bipolar disorder has a genetic component, but the mode of inheritance remains unclear. A previous genome scan conducted in 70 European families led to detect eight regions linked to bipolar disease. Here, we present an investigation of whether the phenotypic heterogeneity of the disorder corresponds to genetic heterogeneity in these regions using additional markers and an extended sample of families. The MLS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Bipolar Disorder

Share to Chromosomes, Human, Pair 2

Share to Data Interpretation, Statistical

Share to Europe

Share to Genetic Heterogeneity

Share to Genetic Linkage

Share to Genetic Markers

Source

Open in PubMed

Identifiers

PMID: 20886542
DOI: 10.1002/ajmg.b.31121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

European collaborative study of early-onset bipolar disorder: Evidence for genetic heterogeneity on 2q14 according to age at onset.PMID 20886542Read ↗

Genome-wide scan for genes involved in bipolar affective disorder in 70 European families ascertained through a bipolar type I early-onset proband: supportive evidence for linkage at 3p14.Semantic proximity Read ↗

Genetic heterogeneity according to age at onset in bipolar disorder: a combined positional cloning and candidate gene approach.Semantic proximity Read ↗

Different familial transmission patterns in bipolar I disorder with onset before and after age 25Semantic proximity Read ↗

Genome‐wide association analysis of age at onset and psychotic symptoms in bipolar disorderSemantic proximity Read ↗

Genetic Risk Score Analysis in Early-Onset Bipolar Disorder.Semantic proximity Read ↗

Early and late onset bipolar disorders: two different forms of manic-depressive illness?Semantic proximity Read ↗

Early onset bipolar disorder: possible linkage to chromosome 9q34.Semantic proximity Read ↗

Association between genetic variation in the myo-inositol monophosphatase 2 (IMPA2) gene and age at onset of bipolar disorder.Semantic proximity Read ↗

Three potential susceptibility loci shown by a genome-wide scan for regions influencing the age at onset of mania.Semantic proximity Read ↗

Age-at-onset in bipolar-I disorder: Mixture analysis of 1369 cases identifies three distinct clinical sub-groupsSemantic proximity Read ↗

Genome-wide association study of early-onset bipolar I disorder in the Han Taiwanese population.Semantic proximity Read ↗

Contrasting genetic burden for bipolar disorder: Early onset versus late onset in an older adult bipolar disorder sample.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.