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Article

Genome‐wide association analysis of age at onset and psychotic symptoms in bipolar disorder

8 Feb 2011

Abstract excerpt

Genome-wide association studies (GWAS) have identified several susceptibility loci for bipolar disorder (BP), most notably ANK3. However, most of the inherited risk for BP remains unexplained. One reason for the limited success may be the genetic heterogeneity of BP. Clinical sub-phenotypes of BP may identify more etiologically homogeneous subsets of patients, which can be studied with increased power to detect...

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PMID: 21305692
DOI: 10.1002/ajmg.b.31172

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