Association of genetic variation in CACNA1C with bipolar disorder in Han Chinese.

doi:10.1016/j.jad.2013.04.004

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Article

Association of genetic variation in CACNA1C with bipolar disorder in Han Chinese.

Journal of affective disorders - 5 Sept 2013

Zhang Xu, Zhang Chen, Wu Zhiguo, Wang Zuowei, Peng Daihui, Chen Jun, Hong Wu, Yuan Chengmei, Li Zezhi, Yu Shunying, Fang Yiru

Abstract excerpt

BACKGROUND: A growing body of evidence highlights the existence of shared genetic susceptibility to both major depressive disorder (MDD) and bipolar disorder (BD), suggesting some potential genetic overlap between the disorders. Genome-wide association studies have identified consistent association of single nucleotide polymorphisms of the α-1 C subunit of the L-type voltage-gated calcium channel gene (CACNA1C)...

Topics

Adult
Age of Onset
Asian People
Bipolar Disorder
Calcium Channels, L-Type
Case-Control Studies
Depressive Disorder, Major
Female
Genetic Predisposition to Disease
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genome-Wide Association Study

Genotype

Humans

Male

Middle Aged

Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 23680436
DOI: 10.1016/j.jad.2013.04.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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