Article
Association of genetic variation in CACNA1C with bipolar disorder in Han Chinese.
Journal of affective disorders - 5 Sept 2013
Zhang Xu, Zhang Chen, Wu Zhiguo, Wang Zuowei, Peng Daihui, Chen Jun, Hong Wu, Yuan Chengmei, Li Zezhi, Yu Shunying, Fang Yiru
Abstract excerpt
BACKGROUND: A growing body of evidence highlights the existence of shared genetic susceptibility to both major depressive disorder (MDD) and bipolar disorder (BD), suggesting some potential genetic overlap between the disorders. Genome-wide association studies have identified consistent association of single nucleotide polymorphisms of the α-1 C subunit of the L-type voltage-gated calcium channel gene (CACNA1C)...
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