Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gemistocytes in newly diagnosed glioblastoma multiforme: Clinical significance and practical implications in the modern era.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Jun 2021

Laviv Yosef, Berkowitz Sharon, Kanner Andrew K, Fichman Suzana, Benouaich-Amiel Alexandra, Siegal Tali, Yust-Katz Shlomit

Abstract excerpt

BACKGROUND: Gemistocytes (GCs) in low grade gliomas are associated with rapid growth and worse prognosis. However, their clinical significance in glioblastomas (GBM) is a matter of debate. AIM OF STUDY: To investigate the clinical significance of the presence of GCs in newly-diagnosed GBM patients in the modern era. METHODS: Computerized medical records from newly diagnosed GBM patients were retrospectively...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioblastoma

Share to Isocitrate Dehydrogenase

Share to Mutation

Share to Prognosis

Source

Identifiers

PMID: 33992170
DOI: 10.1016/j.jocn.2021.03.034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gemistocytes in newly diagnosed glioblastoma multiforme: Clinical significance and practical implications in the modern era.PMID 33992170Read ↗

A clinical evaluation of cystic features in patients with newly diagnosed glioblastoma with IDH-wildtype.Semantic proximity Read ↗

Cytogenetic and Molecular Characterization of IDH-Wildtype Glioblastomas and Grade 4 IDH-Mutant Astrocytomas with Unusual Histology.Semantic proximity Read ↗

Glioblastoma with PNET-like components has a higher frequency of isocitrate dehydrogenase 1 (IDH1) mutation and likely a better prognosis than primary glioblastoma.Semantic proximity Read ↗

IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and NF1 alterations and hypermutation.Semantic proximity Read ↗

Hypoxia-induced polypoid giant cancer cells in glioma promote the transformation of tumor-associated macrophages to a tumor-supportive phenotype.Semantic proximity Read ↗

Histopathological and molecular characteristics of IDH-wildtype glioblastoma without contrast enhancement: Implications for clinical outcomes.Semantic proximity Read ↗

DNA methylation-based analysis reveals accelerated epigenetic aging in giant cell-enriched adult-type glioblastomaSemantic proximity Read ↗

Giant cell glioblastoma is a distinctive subtype of glioma characterized by vulnerability to DNA damage.Semantic proximity Read ↗

Stemness Marker Detection in the Periphery of Glioblastoma and Ability of Glioblastoma to Generate Glioma Stem Cells: Clinical Correlations.Semantic proximity Read ↗

Differential Predictors and Clinical Implications Associated With Long-Term Survivors in IDH Wildtype and Mutant GlioblastomaSemantic proximity Read ↗

The Diagnostic Value of Preoperative Hematology Makers in the Classification and Molecular Subtypes of Newly Diagnosed High-Grade GliomasSemantic proximity Read ↗

Early Detection of Glioma: Investigating Inflammatory Markers (CRP), Kidney, and Liver Function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.