Article
Glioblastoma with PNET-like components has a higher frequency of isocitrate dehydrogenase 1 (IDH1) mutation and likely a better prognosis than primary glioblastoma.
International journal of clinical and experimental pathology - 1 Jan 2011
Song Xianyuan, Andrew Allen R, Terence Dunn S, Fung Kar-Ming, Farmer Peter, Gandhi Shital, Ranjan Tulika, Demopoulos Alexis, Symons Marc, Schulder Michael, Li Jian Yi
Abstract excerpt
Glioblastoma with primitive neuroectodermal tumor-like components (GBM-PNET), a rare variant of glioblastoma, poses both diagnostic and therapeutic challenges. Ten patients with GBM-PNET were investigated with a median age of 51.5 years and the male to female ratio of 4:1. The majority of patients (7 out of 10) showed ring-enhancing lesions on magnetic resonance imaging (MRI), which is classic for GBMs....
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