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Article

The effect of dipeptidyl peptidase IV on disease-associated microglia phenotypic transformation in epilepsy.

Journal of neuroinflammation - 11 May 2021

Zheng Zhicheng, Liang Peiyu, Hou Baohua, Lu Xin, Ma Qianwen, Yu Xiaomin, Han Song, Peng Biwen, Chen Taoxiang, Liu Wanhong, Yin Jun, He Xiaohua

Abstract excerpt

BACKGROUND: Accumulating evidence suggests that disease-associated microglia (DAM), a recently discovered subset of microglia, plays a protective role in neurological diseases. Targeting DAM phenotypic transformation may provide new therapeutic options. However, the relationship between DAM and epilepsy remains unknown. METHODS: Analysis of public RNA-sequencing data revealed predisposing factors (such as...

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Share to Cell Differentiation
Share to Dipeptidyl-Peptidases and Tripeptidyl-Peptidases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mice, Inbred C57BL

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Share to Neuroinflammation and Neurodegeneration Mechanisms

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Source

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Identifiers

PMID: 33975617
DOI: 10.1186/s12974-021-02133-y
PMCID: PMC8114532

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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