Article
Genetic features and efficacy of decitabine-based chemotherapy in elderly patients with acute myeloid leukemia.
Hematology (Amsterdam, Netherlands) - 1 Dec 2021
Wang Bianhong, Guan Wei, Lv Na, Li Ting, Yu Fan, Huang Yuehua, Wang Yanying, Li Lihong, Yu Li
Abstract excerpt
OBJECTIVES: The outcome of elderly acute myeloid leukemia (AML) patients is poor, which was traditionally attributed to patient- and leukemia-related factors. However, studies about the genetic features of these elderly patients have not been integrated and the genetic mechanism of their poor outcome is less known. METHODS: Here, we used next generation sequencing (NGS) to identify the genetic features of elderly...
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