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Article

The prognostic impact of reduced variant burden in elderly patients with acute myeloid leukemia treated with decitabine.

The Korean journal of internal medicine - 1 Jul 2023

Kim Mihee, Kim TaeHyung, Ahn Seo-Yeon, Lee Jun Hyung, Park Ju Heon, Shin Myung-Geun, Jung Sung-Hoon, Song Ga-Young, Yang Deok-Hwan, Lee Je-Jung, Choi Seung Hyun, Kim Mi Yeon, Ahn Jae-Sook, Kim Hyeoung-Joon, Kim Dennis Dong Hwan

Abstract excerpt

BACKGROUND/AIMS: We evaluated the role of next-generation sequencing (NGS)-based disease monitoring for elderly patients diagnosed with acute myeloid leukemia (AML) who received decitabine therapy. METHODS: A total of 123 patients aged > 65 years with AML who received decitabine were eligible. We analyzed the dynamics of variant allele frequency (VAF) in 49 available follow-up samples after the fourth cycle of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37291838
DOI: 10.3904/kjim.2022.396
PMCID: PMC10338247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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